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Mohammad Sulieman

Medical Lab Specialist - Hematology & Immunohematology Founder of MLS GATE

Evaluation of Renal Function and Plasma Osmolality among Covid-19 Patients in Sudan 

This study investigated the effects of COVID-19 on kidney function and plasma osmolality in patients in Sudan. 50 COVID-19 positive patients were compared to 50 healthy controls. Levels of urea, creatinine, estimated glomerular filtration rate (eGFR) and electrolytes were measured in patients on days 1 and 7 of hospital admission. Results showed COVID-19 patients had significantly increased urea and creatinine with lower eGFR versus controls, indicating impaired kidney function. These markers negatively correlated with increasing disease severity. Additionally, COVID-19 patients exhibited significantly reduced plasma osmolality compared to healthy controls, which also correlated with declining eGFR. Overall, the findings demonstrate COVID-19 can damage the kidneys and disrupt fluid/electrolyte balance, requiring close monitoring of renal parameters.

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